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http://purl.uniprot.org/citations/12459324http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
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Background

Variability in salivary proteins and their posttranslational modifications may play an important role in determining their protective features against dental caries. Knowledge of molecular content of saliva in different populations is important for a better understanding of protective properties of this biological fluid. Aims of this study were to analyze electrophoretic pattern and protein composition in resting human whole saliva (HWS) of a Mexican population and to correlate these data with decayed, missing, and filled teeth (DMFT) index in these subjects.

Methods

Resting human whole saliva samples were collected from 120 healthy Mexican dental students. Salivary flow rate, protein concentration, and electrophoretic profile analyzed qualitatively by sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE) were correlated with DMFT index. Gels were successively triple-stained with Coomassie brilliant blue R250, periodic acid Schiff (PAS), silver stain, and salivary molecules were scored as absent (-), present (+/-), and high intensity and size (+).

Results

These showed no substantial differences in number of bands between males and females; however, a slight correlation between total protein concentration and sex was found (p ConclusionsThis study concludes that genetic phenotypic polymorphism is present in the population studied and has correlations with oral health. We found specific characteristics and individual variability in number, intensity, and apparent molecular weight of band features in this Mexican population. These studies provide the initial step for creating an HWS database in this population."xsd:string
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http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/author"Aceves-Luna E."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/author"Banderas-Tarabay J.A."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/author"Garduno-Estrada R."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/author"Gonzalez-Begne M."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/author"Zacarias-D'Oleire I.G."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/name"Arch Med Res"xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/pages"499-505"xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/title"Electrophoretic analysis of whole saliva and prevalence of dental caries. A study in Mexican dental students."xsd:string
http://purl.uniprot.org/citations/12459324http://purl.uniprot.org/core/volume"33"xsd:string
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