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http://purl.uniprot.org/citations/12460919http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12460919http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12460919http://www.w3.org/2000/01/rdf-schema#comment"Mutations of the BRAF protein serine/threonine kinase gene have recently been identified in a variety of human cancers, most notably melanomas. We sought to determine the frequency of BRAF mutations in human lung cancer pathogenesis. Analysis of BRAF sequence from 127 primary human lung adenocarcinomas revealed mutations in two tumor specimens, one in exon 11 (G465V), and a second in exon 15 (L596R). These specimens belong to the same adenocarcinoma subgroup as defined by clustering of gene expression data. BRAF may provide a target for anticancer chemotherapy in a subset of lung adenocarcinoma patients."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Meyerson M."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Meyerson M."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Chen T.-H."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Chen T.-H."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Richards W.G."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Richards W.G."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Naoki K."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Naoki K."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Sugarbaker D.J."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/author"Sugarbaker D.J."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/name"Cancer Res."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/name"Cancer Res."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/pages"7001-7003"xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/pages"7001-7003"xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/title"Missense mutations of the BRAF gene in human lung adenocarcinoma."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/title"Missense mutations of the BRAF gene in human lung adenocarcinoma."xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/volume"62"xsd:string
http://purl.uniprot.org/citations/12460919http://purl.uniprot.org/core/volume"62"xsd:string
http://purl.uniprot.org/citations/12460919http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12460919
http://purl.uniprot.org/citations/12460919http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12460919