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http://purl.uniprot.org/citations/12481038http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12481038http://www.w3.org/2000/01/rdf-schema#comment"Synaptojanin 1 is a polyphosphoinositide phosphatase implicated in synaptic vesicle recycling. We used FM1-43 imaging and electron microscopy in cultured cortical neurons from control and synaptojanin 1 knockout mice to study how the absence of this protein affects specific steps of the synaptic vesicle cycle. Exoendocytosis after a moderate stimulus was unchanged. However, during prolonged stimulation, the regeneration of fusion-competent synaptic vesicles was severely impaired. In stimulated nerve terminals, there was a persistent accumulation of clathrin-coated vesicles and a backup of newly reformed vesicles in the cytomatrix-rich area around the synaptic vesicle cluster. These findings demonstrate that synaptojanin 1 function is needed for the progression of recycling vesicles to the functional synaptic vesicle pool."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.org/dc/terms/identifier"doi:10.1073/pnas.222657399"xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"Chang S."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"Kim W.T."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"Di Paolo G."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"De Camilli P."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"Cremona O."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/author"Daniell L."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/name"Proc Natl Acad Sci U S A"xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/pages"17143-17148"xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/title"Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice."xsd:string
http://purl.uniprot.org/citations/12481038http://purl.uniprot.org/core/volume"99"xsd:string
http://purl.uniprot.org/citations/12481038http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12481038
http://purl.uniprot.org/citations/12481038http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12481038
http://purl.uniprot.org/uniprot/Q8CHC4#attribution-59FAAB930C0F63B6BCA8D74BD15C300Ahttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/12481038
http://purl.uniprot.org/uniprot/#_D3Z1M7-mappedCitation-12481038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12481038
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http://purl.uniprot.org/uniprot/#_D3Z656-mappedCitation-12481038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12481038
http://purl.uniprot.org/uniprot/#_F6VSS8-mappedCitation-12481038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12481038
http://purl.uniprot.org/uniprot/#_F7BQW7-mappedCitation-12481038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12481038