http://purl.uniprot.org/citations/12489177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12489177 | http://www.w3.org/2000/01/rdf-schema#comment | "Two highly expressed noncollagenous proteins associated with dentin mineralization, dentin sialoprotein (DSP) and phosphophoryn (PP), are encoded by a single DSP-PP transcript. To better understand how DSP-PP transcripts are regulated, we have determined the DSP-PP transcription start site, sequenced its 5' flanking region, and analyzed the transcriptional activity of the gene promoter out to -1615 bp. Comparison of the rat cDNA sequence with the mouse, rat and human genes clearly indicates high sequence conservation within the DSP-PP 5' flanking region, implicating the possible presence of highly conserved gene regulatory cis elements. Among a number of conserved transcription sites identified in the 5' flanking region, we demonstrate that the conserved Y box sequence (ATTGG) can specifically bind nuclear extracts from mouse MDPC23 cells. This sequence (located within the -57 bp/-52 bp 5' flanking region) therefore likely represents one DSP-PP transcriptional regulatory sequence."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.org/dc/terms/identifier | "doi:10.1080/03008200290001041"xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/author | "Li X.R."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/author | "Wang L.H."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/author | "Hanks C.T."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/author | "Ritchie H.H."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/author | "Knudtson K."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/name | "Connect Tissue Res"xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/pages | "331-337"xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/title | "The conservation and regulation of rat DSP-PP gene."xsd:string |
http://purl.uniprot.org/citations/12489177 | http://purl.uniprot.org/core/volume | "43"xsd:string |
http://purl.uniprot.org/citations/12489177 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12489177 |
http://purl.uniprot.org/citations/12489177 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12489177 |
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http://purl.uniprot.org/uniprot/A6K5T0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12489177 |