| http://purl.uniprot.org/citations/12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12490194 | http://www.w3.org/2000/01/rdf-schema#comment | "Wnt proteins transmit myriad intercellular signals crucial for the development and homeostasis of metazoan animals from Hydra to human. Abnormal Wnt signaling causes a growing number of diseases, including cancer and osteoporosis. Depending on the context, a given Wnt signal may denote: cell proliferation or apoptosis; cell fate determination, differentiation, or stem cell maintenance; a variety of changes in cell behavior; and/or coordinated interactions with its neighbors. Which event(s) occur in Wnt-responsive cells depends critically on the ability of Dishevelled (Dsh)/Dvl proteins to interpret distinct types of intracellular, receptor-generated stimuli and transmit them to at least two distinct sets of effector molecules, all while apparently ignoring a third type of Wnt-generated Ca(2+) signal. The three conserved domains present in Dsh/Dvl proteins uniquely function in each Wnt pathway, in part by association with 18 (and counting) Dsh/Dvl-associated proteins. The latest data suggest that Dsh/Dvl proteins organize dynamic, pathway-specific subcellular signaling complexes that ensure correct information routing, signal amplification, and dynamic control through feedback regulation. The biochemical and cell biological mechanisms by which Dsh/Dvl proteins accomplish these remarkable tasks remain obscure."xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2002.0869"xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/author | "Wharton K.A. Jr."xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/pages | "1-17"xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/title | "Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction."xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://purl.uniprot.org/core/volume | "253"xsd:string |
| http://purl.uniprot.org/citations/12490194 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12490194 |
| http://purl.uniprot.org/citations/12490194 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12490194 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHW0-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEN4-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A4V3M5-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A4V4C1-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A1Z7N9-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A4V2B8-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_B7Z0S0-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_B7Z0W0-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A1Z6W3-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A1ZBL5-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A1ZBL7-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_A1ZBL9-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_E1JJI5-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |
| http://purl.uniprot.org/uniprot/#_M9NGA3-mappedCitation-12490194 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12490194 |