| http://purl.uniprot.org/citations/12496176 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12496176 | http://www.w3.org/2000/01/rdf-schema#comment | "Ureaplasma urealyticum is the microorganism most frequently isolated from amniotic fluids of women in preterm labor. The relationship between vaginal colonization with U. urealyticum, vaginal interleukin-1 receptor antagonist (IL-1ra) levels, and the IL-1ra genotype in pregnant women was examined. Vaginal specimens, obtained with a cotton swab from 207 women in their first trimester of pregnancy, were tested for IL-1ra concentrations by enzyme-linked immunosorbent assay and for U. urealyticum and IL-1ra genotypes by PCR. U. urealyticum was detected in 85 (41.1%) women. The median IL-1ra level was 450 ng/ml in women positive for U. urealyticum, as opposed to 225 ng/ml in women negative for this microorganism (P < 0.0001). Sixty-two percent of the 16 women who were homozygous for allele 2 of the IL-1ra gene (IL-1RN*2) were colonized with U. urealyticum, as opposed to 47% of the 49 women who were IL-1RN*1/IL-1RN*2 heterozygotes and 34% of the 133 women who were IL-1RN*1 homozygotes (P < 0.05). Median IL-1ra levels were 750 ng/ml in IL-1RN*2 homozygotes, 300 ng/ml in IL-1RN*1/IL-1RN*2 heterozygotes, and 250 ng/ml in IL-1RN*1 homozygotes (P = 0.02). The vast majority of subjects had an uneventful pregnancy and delivered a healthy infant at term. The IL-1ra genotype or U. urealyticum colonization was unrelated to birth weight. Pregnant women who are colonized with U. urealyticum during the first trimester have elevated vaginal IL-1ra concentrations and a higher prevalence of the IL-1RN*2 homozygote genotype than do noncolonized women."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.org/dc/terms/identifier | "doi:10.1128/iai.71.1.271-274.2003"xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/author | "Gerber S."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/author | "Witkin S.S."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/author | "Barton P.T."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/author | "Skupski D.W."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/name | "Infect Immun"xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/pages | "271-274"xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/title | "Interleukin-1 receptor antagonist gene polymorphism, vaginal interleukin-1 receptor antagonist concentrations, and vaginal ureaplasma urealyticum colonization in pregnant women."xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://purl.uniprot.org/core/volume | "71"xsd:string |
| http://purl.uniprot.org/citations/12496176 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12496176 |
| http://purl.uniprot.org/citations/12496176 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12496176 |
| http://purl.uniprot.org/uniprot/#_P18510-mappedCitation-12496176 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12496176 |
| http://purl.uniprot.org/uniprot/#_Q9UP87-mappedCitation-12496176 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12496176 |
| http://purl.uniprot.org/uniprot/Q9UP87 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12496176 |
| http://purl.uniprot.org/uniprot/P18510 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12496176 |