| http://purl.uniprot.org/citations/12526806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12526806 | http://www.w3.org/2000/01/rdf-schema#comment | "Analysis of meiotic recombination by functional genomic approaches reveals prominent spatial and functional interactions among diverse organizational determinants. Recombination occurs between chromatin loop sequences; however, these sequences are spatially tethered to underlying chromosome axes via their recombinosomes. Meiotic chromosomal protein, Red1, localizes to chromosome axes; however, Red1 loading is modulated by R/G-bands isochores and thus by bulk chromatin state. Recombination is also modulated by isochore determinants: R-bands differentially favor double-strand break (DSB) formation but disfavor subsequent loading of meiotic RecA homolog, Dmc1. Red1 promotes DSB formation in both R- and G-bands and then promotes Dmc1 loading, specifically counteracting disfavoring R-band effects. These complexities are discussed in the context of chiasma formation as a series of coordinated local changes at the DNA and chromosome-axis levels."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(02)01167-4"xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/author | "Hunter N."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/author | "Blat Y."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/author | "Kleckner N."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/author | "Protacio R.U."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/pages | "791-802"xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/title | "Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation."xsd:string |
| http://purl.uniprot.org/citations/12526806 | http://purl.uniprot.org/core/volume | "111"xsd:string |
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| http://purl.uniprot.org/uniprot/P14291#attribution-EEBD5A55AA7A4BF8AB88DE57DDD37F0A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12526806 |
| http://purl.uniprot.org/uniprot/#_P14291-mappedCitation-12526806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12526806 |
| http://purl.uniprot.org/uniprot/#_P25453-mappedCitation-12526806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12526806 |
| http://purl.uniprot.org/uniprot/P25453 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12526806 |
| http://purl.uniprot.org/uniprot/P14291 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12526806 |