| http://purl.uniprot.org/citations/12543146 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12543146 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12543146 | http://www.w3.org/2000/01/rdf-schema#comment | "The origin recognition complex (ORC) is a multisubunit protein composed of six polypeptides that binds to replication origins and is essential for the initiation of chromosomal DNA replication. Using the Vectorette technique, we have isolated a novel gene encoding an ORC1-like protein from the human malaria parasite Plasmodium falciparum. The gene has no introns and encodes a protein (PfORC1) of 1189 amino acid residues with a predicted molecular mass of 139 kDa. PfORC1 contains all conserved sequences in the ORC1/Cdc6/Cdc18 family and displays the highest homology to the Schizosaccharomyces pombe ORC1. However, PfORC1 possesses an extensive N-terminal segment with several interesting features including multiple potential phosphorylation sites, a large proportion of charged amino acids, four copies of a heptamer repeat, two nuclear localisation signals, and a leucine zipper motif. Southern blot analyses show that the Pforc1 gene is present as a single copy per haploid genome and is located on chromosome 12. A 5600 nucleotide transcript of this gene is expressed predominantly in the sexual erythrocytic stage, indicating that PfORC1 may be involved in gametogenesis during which DNA is quickly replicated."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1383-5769(02)00079-x"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1383-5769(02)00079-x"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/author | "Cox L.S."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/author | "Cox L.S."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/author | "Li J.-L."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/author | "Li J.-L."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/name | "Parasitol. Int."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/name | "Parasitol. Int."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/pages | "41-52"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/pages | "41-52"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/title | "Characterisation of a sexual stage-specific gene encoding ORC1 homologue in the human malaria parasite Plasmodium falciparum."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/title | "Characterisation of a sexual stage-specific gene encoding ORC1 homologue in the human malaria parasite Plasmodium falciparum."xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/12543146 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12543146 |
| http://purl.uniprot.org/citations/12543146 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12543146 |
| http://purl.uniprot.org/citations/12543146 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12543146 |
| http://purl.uniprot.org/citations/12543146 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12543146 |
| http://purl.uniprot.org/uniprot/Q8I615 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12543146 |
| http://purl.uniprot.org/uniprot/Q8I615#attribution-C5BF90FB45E66C8ACAA6741D924311A5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12543146 |