| http://purl.uniprot.org/citations/12552446 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12552446 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12552446 | http://www.w3.org/2000/01/rdf-schema#comment | "The relationship among CCR5 genotype, cytomegalovirus infection, and disease progression and death was studied among 159 human immunodeficiency virus (HIV)-infected patients with hemophilia. One patient (0.6%) had the CCR5Delta32/CCR5Delta32 genotype (which occurs in approximately 2% of the Scandinavian population) and a rapid disease course. His HIV V3 region contained genotypic features attributable to X4 virus and resembled functionally verified X4 virus and virus from patients treated with a CD4 cell-stimulating drug, tucaresol. Age-related differences in disease progression rate and survival time were seen for CCR5/CCR5 patients. Surprisingly, no protective effect of the CCR5/CCR5Delta32 genotype on disease progression or survival was seen for children but was evident for adults. Age group-related immunologic differences might explain this variation, and transmission route and/or viral phenotype variation within donor virus may be related to the limited protection of the CCR5Delta32/CCR5Delta32 genotype. Sequence comparisons indicate that X4 virus can be selected in vivo due to either absence of CCR5 receptors or relative increase of CXCR4 receptors."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.org/dc/terms/identifier | "doi:10.1086/345881"xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.org/dc/terms/identifier | "doi:10.1086/345881"xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Eugen-Olsen J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Eugen-Olsen J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Fugger L."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Fugger L."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Svejgaard A."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Svejgaard A."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Schulman S."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Schulman S."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Gerstoft J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Gerstoft J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Ingerslev J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Ingerslev J."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Berntorp E."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Berntorp E."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Iversen A.K."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Iversen A.K."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Tengborn L."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Tengborn L."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Scheibel E."xsd:string |
| http://purl.uniprot.org/citations/12552446 | http://purl.uniprot.org/core/author | "Scheibel E."xsd:string |