http://purl.uniprot.org/citations/12576445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12576445 | http://www.w3.org/2000/01/rdf-schema#comment | "Lipophilin B mRNA is overexpressed in approximately 70% of breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. This is further supported by the recent finding that, like other members of the secretoglobulin-uteroglobin family, mammaglobin and lipophilin B form a heteroduplex. The studies described show that there are pre-existing antibodies to lipophilin B peptide in the sera of breast cancer patients with different stages and grade of tumor and that this response is different from that seen to recombinant mammaglobin and native mammaglobin-lipophilin B complex. The highest titers were observed in later stage tumors. In addition, low levels of antibody were also seen in some patients with prostate and ovarian cancers, consistent with lipophilin B mRNA expression in these tumors at lower abundance than in breast tumors. In contrast, lipophilin B antibodies were absent in 20 healthy donor sera and 30 lung cancer sera. A polymorphism identified in Lipophilin B did not appear to influence human sera reactivity. The data indicate that humoral immune responses to lipophilin B may serve as a diagnostic indicator, particularly for breast cancer."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Vedvick T.S."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Reed S.G."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Carter D."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Persing D.H."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Sleath P.R."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Dillon D.C."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Houghton R.L."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Reynolds L.D."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "McNeill P.D."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Retter M.W."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Fanger G."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/author | "Molesh D.A."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/name | "Clin Cancer Res"xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/pages | "749-754"xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/title | "Serum antibodies to lipophilin B detected in late stage breast cancer patients."xsd:string |
http://purl.uniprot.org/citations/12576445 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/12576445 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12576445 |
http://purl.uniprot.org/citations/12576445 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12576445 |
http://purl.uniprot.org/uniprot/#_O95969-mappedCitation-12576445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12576445 |
http://purl.uniprot.org/uniprot/O95969 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12576445 |