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http://purl.uniprot.org/citations/12576445http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12576445http://www.w3.org/2000/01/rdf-schema#comment"Lipophilin B mRNA is overexpressed in approximately 70% of breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. This is further supported by the recent finding that, like other members of the secretoglobulin-uteroglobin family, mammaglobin and lipophilin B form a heteroduplex. The studies described show that there are pre-existing antibodies to lipophilin B peptide in the sera of breast cancer patients with different stages and grade of tumor and that this response is different from that seen to recombinant mammaglobin and native mammaglobin-lipophilin B complex. The highest titers were observed in later stage tumors. In addition, low levels of antibody were also seen in some patients with prostate and ovarian cancers, consistent with lipophilin B mRNA expression in these tumors at lower abundance than in breast tumors. In contrast, lipophilin B antibodies were absent in 20 healthy donor sera and 30 lung cancer sera. A polymorphism identified in Lipophilin B did not appear to influence human sera reactivity. The data indicate that humoral immune responses to lipophilin B may serve as a diagnostic indicator, particularly for breast cancer."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Vedvick T.S."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Reed S.G."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Carter D."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Persing D.H."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Sleath P.R."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Dillon D.C."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Houghton R.L."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Reynolds L.D."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"McNeill P.D."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Retter M.W."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Fanger G."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/author"Molesh D.A."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/name"Clin Cancer Res"xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/pages"749-754"xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/title"Serum antibodies to lipophilin B detected in late stage breast cancer patients."xsd:string
http://purl.uniprot.org/citations/12576445http://purl.uniprot.org/core/volume"9"xsd:string
http://purl.uniprot.org/citations/12576445http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12576445
http://purl.uniprot.org/citations/12576445http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12576445
http://purl.uniprot.org/uniprot/#_O95969-mappedCitation-12576445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12576445
http://purl.uniprot.org/uniprot/O95969http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/12576445