| http://purl.uniprot.org/citations/12577064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12577064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12577064 | http://www.w3.org/2000/01/rdf-schema#comment | "Early endosomes move bidirectionally between the cell periphery and the interior through a mechanism regulated by the low molecular weight GTPase RhoD. Here, we identify a novel splice variant of human Diaphanous, hDia2C, which specifically binds to RhoD and is recruited onto early endosomes. Expression of RhoD and hDia2C induces a striking alignment of early endosomes along actin filaments and reduces their motility. This activity depends on the membrane recruitment and activation of c-Src kinase, thus uncovering a new role in endosome function. Our results define a novel signal transduction pathway, in which hDia2C and c-Src are sequentially activated by RhoD to regulate the motility of early endosomes through interactions with the actin cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb935"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb935"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Zerial M."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Zerial M."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Kalaidzidis Y."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Kalaidzidis Y."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Gasman S."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/author | "Gasman S."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/pages | "195-204"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/pages | "195-204"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/title | "RhoD regulates endosome dynamics through diaphanous-related formin and Src tyrosine kinase."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/title | "RhoD regulates endosome dynamics through diaphanous-related formin and Src tyrosine kinase."xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/12577064 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12577064 |
| http://purl.uniprot.org/citations/12577064 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12577064 |
| http://purl.uniprot.org/citations/12577064 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12577064 |
| http://purl.uniprot.org/citations/12577064 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12577064 |