| http://purl.uniprot.org/citations/12594045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12594045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12594045 | http://www.w3.org/2000/01/rdf-schema#comment | "The splicing of nascent mRNA precursors is an essential step for the expression of all intron-containing eukaryotic genes. Removal of intron sequences from nascent transcripts is mediated by the spliceosome, a large multicomponent complex. We describe here the identification of two genes encoding related, putative splicing factors on human chromosome 19p13.11, SF4 (splicing factor 4) and SFRS14 (splicing factor arginine/serine-rich 14). Both genes encode proteins containing a SURP motif; this domain is found in several splicing proteins including Drosophila alternative splicing regulator, suppressor-of-white-apricot (SWAP) and the yeast splicing factor, prp21p. In addition, SF4 and SFRS14 contain a G-patch domain at their C-termini, a motif present in a large number of eukaryotic RNA-binding proteins. SFRS14 also contains an N-terminal region that is rich in arginine/serine residues, suggesting SFRS14 is a novel member of the SR-related family of pre-mRNA processing factors. We have also identified the mouse orthologues of SF4 and SFRS14, based on conserved domain organization and high sequence similarity. Interestingly, SFRS14 undergoes alternative 3'-end processing events that are conserved between human and mouse, suggesting a functional significance."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(02)01230-1"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(02)01230-1"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/author | "Hewitt J.E."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/author | "Hewitt J.E."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/author | "Sampson N.D."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/author | "Sampson N.D."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/pages | "91-100"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/pages | "91-100"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/title | "SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/title | "SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11."xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/volume | "305"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://purl.uniprot.org/core/volume | "305"xsd:string |
| http://purl.uniprot.org/citations/12594045 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12594045 |
| http://purl.uniprot.org/citations/12594045 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12594045 |
| http://purl.uniprot.org/citations/12594045 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12594045 |
| http://purl.uniprot.org/citations/12594045 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12594045 |
| http://purl.uniprot.org/embl-cds/AAN77123.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12594045 |
| http://purl.uniprot.org/uniprot/Q8IWZ8 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12594045 |