http://purl.uniprot.org/citations/1259717 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1259717 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1259717 | http://www.w3.org/2000/01/rdf-schema#comment | "Aipysurus laevis venom was chromatographed on CM-cellulose and Bio-Rex 70 columns. Three neurotoxic components, toxins Aipysurus laevis a, b and c, were isolated. The toxins a, b and c corresponded to 22, 33 and 21% respectively of the proteins in the original venom, and accounted for almost all the lethal activity of the venom. The three toxins a, b and c were monodisperse on disc electrophoresis at pH4; toxins a and b moved at the same velocity and c a little faster. They were monodisperse also on sodium dodecyl sulphate-polyacrylamide-disc-gel electrophoresis, giving a molecular weight of 7600. The molecular weight of toxin b estimated by gel filtration was 7000. The amino acid sequence analyses of these toxins revealed that they consisted of 60 amino acid residues and that Aipysurus laevis b was [25-methionine, 28-arginine] Aipysurus laevis a. Aipysurus laevis c was [28-lysine] Aipysurus laevis a, the tryptic peptide sequence relying on homology. The LD50 values of these toxins for 20g mice were 0.076 mug/g body wt. They inhibited the acetylcholine-induced contracture but did not affect the CKl-induced contracture of the isolated muscle."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj1530079"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj1530079"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/author | "Maeda N."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/author | "Maeda N."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/author | "Tamiya N."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/author | "Tamiya N."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/date | "1976"xsd:gYear |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/date | "1976"xsd:gYear |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/name | "Biochem. J."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/name | "Biochem. J."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/pages | "79-87"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/pages | "79-87"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/title | "Isolation, properties and amino acid sequences of three neurotoxins from the venom of a sea snake, Aipysurus laevis."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/title | "Isolation, properties and amino acid sequences of three neurotoxins from the venom of a sea snake, Aipysurus laevis."xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/volume | "153"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://purl.uniprot.org/core/volume | "153"xsd:string |
http://purl.uniprot.org/citations/1259717 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1259717 |
http://purl.uniprot.org/citations/1259717 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1259717 |
http://purl.uniprot.org/citations/1259717 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1259717 |
http://purl.uniprot.org/citations/1259717 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1259717 |
http://purl.uniprot.org/uniprot/P32879 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1259717 |
http://purl.uniprot.org/uniprot/P19959 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1259717 |