| http://purl.uniprot.org/citations/12615067 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12615067 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12615067 | http://www.w3.org/2000/01/rdf-schema#comment | "Btn2p is a novel coiled coil cytosolic protein in Saccharomyces cerevisiae. We report that Btn2p interacts with Yif1p, a component of a protein complex at the Golgi that functions in ER to Golgi transport. Deletion of Btn2p, btn2-delta, results in mis-localiztion of Yif1p to the vacuole. Therefore, Btn2p may have an apparent role in intracellular trafficking of proteins. Btn2p was originally identified as being up-regulated in a btn1-delta strain, which exhibits dysregulation of vacuolar pH, and this up-regulation of Btn2p was presumed to contribute to maintaining a stable vacuolar pH [Pearce et al. Nat. Genet. 22 (1999) 55]. We propose that up-regulation of Btn2p in btn1-delta is an indicator of altered trafficking within the cell, and as btn1-delta serves as a model for the lysosomal storage disorder Batten disease, that altered intracellular trafficking may contribute to some of the cellular pathological hallmarks of this disease."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(03)00209-2"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(03)00209-2"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Pearce D.A."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Pearce D.A."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Chattopadhyay S."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Chattopadhyay S."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Roberts P.M."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/author | "Roberts P.M."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/pages | "534-538"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/pages | "534-538"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/title | "The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/title | "The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p."xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/volume | "302"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://purl.uniprot.org/core/volume | "302"xsd:string |
| http://purl.uniprot.org/citations/12615067 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12615067 |
| http://purl.uniprot.org/citations/12615067 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12615067 |
| http://purl.uniprot.org/citations/12615067 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12615067 |
| http://purl.uniprot.org/citations/12615067 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12615067 |