http://purl.uniprot.org/citations/12631718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12631718 | http://www.w3.org/2000/01/rdf-schema#comment | "Telomerase-deficient Saccharomyces cerevisiae cells show a progressive decrease in telomere length. When grown for several days in log phase, the tlc1Delta cells initially display wild-type growth kinetics with subsequent loss of growth potential after which survivors are generated via RAD52-dependent homologous recombination. We found that chromosome loss in these telomerase-deficient cells only increased after a significant decline in growth potential of the culture. At earlier stages of growth, as the telomerase-deficient cells began to show loss of growth potential, the cells arrested in G2/M and showed RNR3 induction and Rad53p phosphorylation. These responses were dependent on RAD24 and MEC1, suggesting that short telomeres are recognized as DNA damage and signal G2/M arrest."xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.02-04-0057"xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/author | "Greider C.W."xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/author | "IJpma A.S."xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/pages | "987-1001"xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/title | "Short telomeres induce a DNA damage response in Saccharomyces cerevisiae."xsd:string |
http://purl.uniprot.org/citations/12631718 | http://purl.uniprot.org/core/volume | "14"xsd:string |
http://purl.uniprot.org/citations/12631718 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12631718 |
http://purl.uniprot.org/citations/12631718 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12631718 |
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http://purl.uniprot.org/uniprot/#_P32641-mappedCitation-12631718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12631718 |
http://purl.uniprot.org/uniprot/P06778 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12631718 |
http://purl.uniprot.org/uniprot/P32641 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12631718 |
http://purl.uniprot.org/uniprot/P38111 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12631718 |