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| http://purl.uniprot.org/citations/12633678 | http://www.w3.org/2000/01/rdf-schema#comment | "Phytanic acid (3,7,10,14-tetramethylhexadecanoic acid) is a branched-chain fatty acid which is known to accumulate in a number of different genetic diseases including Refsum disease. Due to the presence of a methyl-group at the 3-position, phytanic acid and other 3-methyl fatty acids can not undergo beta-oxidation but are first subjected to fatty acid alpha-oxidation in which the terminal carboxyl-group is released as CO(2). The mechanism of alpha-oxidation has long remained obscure but has been resolved in recent years. Furthermore, peroxisomes have been found to play an indispensable role in fatty acid alpha-oxidation, and the complete alpha-oxidation machinery is probably localized in peroxisomes. This Review describes the current state of knowledge about fatty acid alpha-oxidation in mammals with particular emphasis on the mechanism involved and the enzymology of the pathway."xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1388-1981(03)00003-9"xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/author | "Wanders R.J."xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/author | "Lloyd M.D."xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/author | "Jansen G.A."xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/pages | "119-135"xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/title | "Phytanic acid alpha-oxidation, new insights into an old problem: a review."xsd:string |
| http://purl.uniprot.org/citations/12633678 | http://purl.uniprot.org/core/volume | "1631"xsd:string |
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