| http://purl.uniprot.org/citations/12637673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12637673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12637673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/12637673 | http://www.w3.org/2000/01/rdf-schema#comment | "Enzymes provide enormous rate enhancements, unmatched by any other type of catalyst. The stabilization of high-energy states along the reaction coordinate is the crux of the catalytic power of enzymes. We report the atomic-resolution structure of a high-energy reaction intermediate stabilized in the active site of an enzyme. Crystallization of phosphorylated beta-phosphoglucomutase in the presence of the Mg(II) cofactor and either of the substrates glucose 1-phosphate or glucose 6-phosphate produced crystals of the enzyme-Mg(II)-glucose 1,6-(bis)phosphate complex, which diffracted x-rays to 1.2 and 1.4 angstroms, respectively. The structure reveals a stabilized pentacovalent phosphorane formed in the phosphoryl transfer from the C(1)O of glucose 1,6-(bis)phosphate to the nucleophilic Asp8 carboxylate."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1082710"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1082710"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1082710"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Allen K.N."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Allen K.N."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Dunaway-Mariano D."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Dunaway-Mariano D."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Zhang G."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Zhang G."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Lahiri S.D."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/author | "Lahiri S.D."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/pages | "2067-2071"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/pages | "2067-2071"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/title | "The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/title | "The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction."xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/volume | "299"xsd:string |
| http://purl.uniprot.org/citations/12637673 | http://purl.uniprot.org/core/volume | "299"xsd:string |