RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12644308http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12644308http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12644308http://www.w3.org/2000/01/rdf-schema#comment"Progesterone acts via two specific receptors to affect gene transcription in target tissues. Progesterone receptor (PR) B contains 933 amino acids while PR A is a truncated version lacking the initial 164 amino acids. We have cloned a novel, truncated PR from both human adipose and aortic cDNA libraries. This cDNA encodes a predicted protein of 314 amino acids, termed PR-M. Initiation of transcription of PR-M occurs in intron 3, with the initial exon identical to exon 4 of the genomic PRs, except for a novel 16 amino acid amino-terminal sequence, consistent with a signal peptide. The remainder of PR-M is identical to the genomic PR. Transcript for this protein was identified by RT-PCR in human aortic endothelial cells and T47D breast cancer cells. Expression of PR-M in Sf 9 insect cells results in a 38-kDa protein, demonstrated in human aortic endothelial cells and T47D breast cancer cells. The function of PR-M remains to be determined. The presence of a signal peptide and the lack of a DNA binding region suggests a non-genomic action."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.org/dc/terms/identifier"doi:10.1016/s0303-7207(02)00380-5"xsd:string
http://purl.uniprot.org/citations/12644308http://purl.org/dc/terms/identifier"doi:10.1016/s0303-7207(02)00380-5"xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Wei Y."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Wei Y."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Zhang F."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Zhang F."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Dupont B."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Dupont B."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Hansen E."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Hansen E."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Price T.M."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Price T.M."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Saner K.J."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Saner K.J."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Welter B.H."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/author"Welter B.H."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/name"Mol. Cell. Endocrinol."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/name"Mol. Cell. Endocrinol."xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/pages"155-163"xsd:string
http://purl.uniprot.org/citations/12644308http://purl.uniprot.org/core/pages"155-163"xsd:string