http://purl.uniprot.org/citations/12654300 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12654300 | http://www.w3.org/2000/01/rdf-schema#comment | "The unc-52 gene of Claenorhabditis elegans encodes a homologue of the basement membrane heparan sulfate proteoglycan perlecan. Viable alleles reduce the abundance of UNC-52 in late larval stages and increase the frequency of distal tip cell (DTC) migration defects caused by mutations disrupting the UNC-6/netrin guidance system. These unc-52 alleles do not cause circumferential DTC migration defects in an otherwise wild-type genetic background. The effects of unc-52 mutations on DTC migrations are distinct from effects on myofilament organization and can be partially suppressed by mutations in several genes encoding growth factor-like molecules, including EGL-17/FGF, UNC-129/TGF-beta, DBL-1/TGF-beta, and EGL-20/WNT. We propose that UNC-52 serves dual roles in C. elegans larval development in the maintenance of muscle structure and the regulation of growth factor-like signaling pathways."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0012-1606(03)00014-9"xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/author | "Kawano T."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/author | "Zheng H."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/author | "Culotti J.G."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/author | "Alves G."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/author | "Merz D.C."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/pages | "173-186"xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/title | "UNC-52/perlecan affects gonadal leader cell migrations in C. elegans hermaphrodites through alterations in growth factor signaling."xsd:string |
http://purl.uniprot.org/citations/12654300 | http://purl.uniprot.org/core/volume | "256"xsd:string |
http://purl.uniprot.org/citations/12654300 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12654300 |
http://purl.uniprot.org/citations/12654300 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12654300 |
http://purl.uniprot.org/uniprot/Q06561#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G348#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/G1K109#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G350#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G353#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/G5EEI5#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G351#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G354#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G349#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |
http://purl.uniprot.org/uniprot/H9G352#attribution-0E12E3C36E739E8FF83D01E44059CB04 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12654300 |