http://purl.uniprot.org/citations/12663813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12663813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12663813 | http://www.w3.org/2000/01/rdf-schema#comment | "Retroviral integration in vivo is mediated by preintegration complexes (PICs) derived from infectious virions. In addition to the integrase enzyme and cDNA substrate, PICs contain a variety of viral and host cell proteins. Whereas two different cell proteins, high-mobility group protein A1 (HMGA1) and the barrier-to-autointegration factor (BAF), were identified as integration cofactors based on activities in in vitro PIC assays, only HMGA1 was previously identified as a PIC component. By using antibodies against known viral and cellular PIC components, we demonstrate here functional coimmunoprecipitation of endogenous BAF protein with human immunodeficiency virus type 1 (HIV-1) PICs. Since integrase protein and integration activity were also coimmunoprecipitated by anti-BAF antibodies, we conclude that BAF is a component of HIV-1 PICs. These data are consistent with the model that BAF functions as an integration cofactor in vivo."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.77.8.5030-5036.2003"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.77.8.5030-5036.2003"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/author | "Engelman A."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/author | "Engelman A."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/author | "Lin C.W."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/author | "Lin C.W."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/pages | "5030-5036"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/pages | "5030-5036"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/title | "The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/title | "The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes."xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/volume | "77"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://purl.uniprot.org/core/volume | "77"xsd:string |
http://purl.uniprot.org/citations/12663813 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12663813 |
http://purl.uniprot.org/citations/12663813 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12663813 |
http://purl.uniprot.org/citations/12663813 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12663813 |
http://purl.uniprot.org/citations/12663813 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12663813 |
http://purl.uniprot.org/uniprot/O75531 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12663813 |
http://purl.uniprot.org/uniprot/O75531#attribution-8E85F292621426118078FDAD0956914C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12663813 |