| http://purl.uniprot.org/citations/12667357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12667357 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo study of the HLA-DQA(1) alleles and environment interaction in type I psoriasis.MethodsUsing case-control study, 144 type I psoriatics and 273 healthy people were investigated. The HLA-DQA(1) alleles were examined by PCR-SSP.Results(1) HLA-DQA(1)*0104 and DQA(1)*0201 alleles were positively associated with type I psoriasis (P(c) < 0.002); HLA-DQA(1)*0501 allele was negatively associated with type I psoriasis (P(c) < 0.000 5). (2) The HLA-DQA(1)*0104 allele and moisture was interaction in type I psoriasis (P = 0.023 8, OR = 5.29). (3) There were no interactions between the HLA-DQA(1)*0201 allele and 10 environmental factors in type I psoriasis. (4) The HLA-DQA(1)*0501 allele, moisture (P = 0.002 4, OR = 7.50), eating fish and shrimp (P = 0.000 4, OR = 12.92), drugs (P = 0.043 3, OR = 9.43) or vaccination (P = 0.043 3, OR = 9.43) were interacted in type I psoriasis.Conclusions(1) HLA-DQA(1)*0104 and DQA(1)*0201 alleles might be the susceptible genes or it may have close linkage with the susceptible gene. HLA-DQA(1)*0501 allele had protective effect against the development of type I psoriasis. (2) The HLA-DQA(1)*0104 and DQA(1)*0501 alleles increased risk possibility of environmental factors in type I psoriasis."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/author | "Gao M."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/author | "Yang S."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/author | "Wei S."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/name | "Zhonghua Liu Xing Bing Xue Za Zhi"xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/pages | "445-448"xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/title | "[Study of the association between HLA-DQA1 alleles and environmental factors in psoriasis]."xsd:string |
| http://purl.uniprot.org/citations/12667357 | http://purl.uniprot.org/core/volume | "23"xsd:string |
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