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http://purl.uniprot.org/citations/12668252http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12668252http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12668252http://www.w3.org/2000/01/rdf-schema#comment"The modulation of BmK AS, a neurotoxic polypeptide from scorpion Buthus martensi Karsch, on the voltage-gated Na(+) channels has been investigated in the B104 neuroblastoma cell line by whole-cell patch clamping. It was found that the whole Na(+) currents and tetrodotoxin-resistant Na(+) current were depressed in a biphasic manner and both steady-state activation and inactivation curves were shifted toward the hyperpolarizing direction in the presence of BmK AS. The results suggested that BmK AS could inhibit both tetrodotoxin-sensitive and -resistant Na(+) currents via modulating the gating mechanism of the voltage-gated Na(+) channels in B104 cells."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3940(03)00094-6"xsd:string
http://purl.uniprot.org/citations/12668252http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3940(03)00094-6"xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Chen J."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Chen J."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Ji Y.-H."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Ji Y.-H."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Feng X.-H."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Feng X.-H."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Shun H.-Y."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Shun H.-Y."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Tan Z.-Y."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/author"Tan Z.-Y."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/name"Neurosci. Lett."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/name"Neurosci. Lett."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/pages"123-126"xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/pages"123-126"xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/title"Modulation of BmK AS, a scorpion neurotoxic polypeptide, on voltage-gated Na+ channels in B104 neuronal cell line."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/title"Modulation of BmK AS, a scorpion neurotoxic polypeptide, on voltage-gated Na+ channels in B104 neuronal cell line."xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/volume"340"xsd:string
http://purl.uniprot.org/citations/12668252http://purl.uniprot.org/core/volume"340"xsd:string