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http://purl.uniprot.org/citations/12671000http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12671000http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12671000http://www.w3.org/2000/01/rdf-schema#comment"We have determined the complete sequence of 951,695 bp from the class I region of H2, the mouse major histocompatibility complex (Mhc) from strain 129/Sv (haplotype bc). The sequence contains 26 genes. The sequence spans from the last 50 kb of the H2-T region, including 2 class I genes and 3 class I pseudogenes, and includes the H2-M region up to Gabbr1. A 500-kb stretch of the H2-M region contains 9 class I genes and 4 pseudogenes, which fall into two subfamilies, M1 and M10, distinct from other mouse class I genes. This M1/M10 class I gene-cluster is separated from the centromeric H2-T and the telomeric H2-M4, -5 and -6 class I genes by "nonclass I genes". Comparison with the corresponding 853-kb region of the human Mhc, which includes the HLA-A region, shows a mosaic of conserved regions of orthologous nonclass I genes separated by regions of species-specific expansion of paralogous Mhc class I genes. The analysis of this mosaic structure illuminates the dynamic evolution of the Mhc class I region among mammals and provides evidence for the framework hypothesis."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.org/dc/terms/identifier"doi:10.1101/gr.975303"xsd:string
http://purl.uniprot.org/citations/12671000http://purl.org/dc/terms/identifier"doi:10.1101/gr.975303"xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Amadou C."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Amadou C."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Evans G.A."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Evans G.A."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Takada T."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Takada T."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Yoshino M."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Yoshino M."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Kumanovics A."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Kumanovics A."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Lindahl K.F."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Lindahl K.F."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Athanasiou M."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Athanasiou M."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Jones E.P."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/author"Jones E.P."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/name"Genome Res."xsd:string
http://purl.uniprot.org/citations/12671000http://purl.uniprot.org/core/name"Genome Res."xsd:string