| http://purl.uniprot.org/citations/12679033 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12679033 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12679033 | http://www.w3.org/2000/01/rdf-schema#comment | "Cell-extracellular matrix adhesion is an important determinant of cell morphology. We show here that migfilin, a LIM-containing protein, localizes to cell-matrix adhesions, associates with actin filaments, and is essential for cell shape modulation. Migfilin interacts with the cell-matrix adhesion protein Mig-2 (mitogen inducible gene-2), a mammalian homolog of UNC-112, and the actin binding protein filamin through its C- and N-terminal domains, respectively. Loss of Mig-2 or migfilin impairs cell shape modulation. Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Migfilin therefore functions as an important scaffold at cell-matrix adhesions. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(03)00163-6"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(03)00163-6"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Shi X."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Shi X."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Tu Y."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Tu Y."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Wu S."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Wu S."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Wu C."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Wu C."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Chen K."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/author | "Chen K."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/pages | "37-47"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/pages | "37-47"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/title | "Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/title | "Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation."xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/volume | "113"xsd:string |
| http://purl.uniprot.org/citations/12679033 | http://purl.uniprot.org/core/volume | "113"xsd:string |