| http://purl.uniprot.org/citations/12690961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12690961 | http://www.w3.org/2000/01/rdf-schema#comment | "Yeast assays for G-protein-coupled receptors have many attractions due to their simplicity, low cost, and lack of endogenous receptors. Since the first report of functional coupling of the human beta 2 adrenergic receptor to the yeast pheromone-response pathway in 1990, the technology has developed to a point at which more than 30 heterologous GPCRs are now published to couple. Major breakthroughs have come from an understanding of receptor-G protein interactions, alongside advances in knowledge of the structure of heterotrimeric G proteins. Yeast screens have been used to identify ligands both from compound collections and through the autocrine expression of peptide libraries. Yeast genetics has also been applied to a functional analysis of GPCRs and peptide ligands. In this review we describe the historical development of yeast GPCR assay systems and their current applications."xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.org/dc/terms/identifier | "doi:10.3109/10606820214647"xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/author | "Brown A.J."xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/author | "Dowell S.J."xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/name | "Recept Channels"xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/pages | "343-352"xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/title | "Yeast assays for G-protein-coupled receptors."xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/12690961 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12690961 |
| http://purl.uniprot.org/citations/12690961 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12690961 |
| http://purl.uniprot.org/uniprot/#_P18851-mappedCitation-12690961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12690961 |
| http://purl.uniprot.org/uniprot/#_P18852-mappedCitation-12690961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12690961 |
| http://purl.uniprot.org/uniprot/#_P08539-mappedCitation-12690961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12690961 |
| http://purl.uniprot.org/uniprot/P08539 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12690961 |
| http://purl.uniprot.org/uniprot/P18852 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12690961 |
| http://purl.uniprot.org/uniprot/P18851 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12690961 |