| http://purl.uniprot.org/citations/12707312 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12707312 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12707312 | http://www.w3.org/2000/01/rdf-schema#comment | "The Aurora B kinase complex is a critical regulator of chromosome segregation and cytokinesis. In Caenorhabditis elegans, AIR-2 (Aurora B) function requires ICP-1 (Incenp) and BIR-1 (Survivin). In various systems, Aurora B binds to orthologues of these proteins. Through genetic analysis, we have identified a new subunit of the Aurora B kinase complex, CSC-1. C. elegans embryos depleted of CSC-1, AIR-2, ICP-1, or BIR-1 have identical phenotypes. CSC-1, BIR-1, and ICP-1 are interdependent for their localization, and all are required for AIR-2 localization. In vitro, CSC-1 binds directly to BIR-1. The CSC-1/BIR-1 complex, but not the individual subunits, associates with ICP-1. CSC-1 associates with ICP-1, BIR-1, and AIR-2 in vivo. ICP-1 dramatically stimulates AIR-2 kinase activity. This activity is not stimulated by CSC-1/BIR-1, suggesting that these two subunits function as targeting subunits for AIR-2 kinase."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200207117"xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200207117"xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Glotzer M."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Glotzer M."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Guse A."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Guse A."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Krascenicova I."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Krascenicova I."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Romano A."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Romano A."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Schnabel H."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Schnabel H."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Schnabel R."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/author | "Schnabel R."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/pages | "229-236"xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/pages | "229-236"xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/title | "CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1."xsd:string |
| http://purl.uniprot.org/citations/12707312 | http://purl.uniprot.org/core/title | "CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1."xsd:string |