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http://purl.uniprot.org/citations/12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12714268http://www.w3.org/2000/01/rdf-schema#comment"Polymorphism of the human leukocyte antigen has been implicated in a number of autoimmune disorders including ageing. In the course of the present study, no association of the human leukocyte antigen (HLA)-A1, B8, DR3 haplotype with a male Irish aged population, as previously reported, was observed. Two polymorphic nucleotides in the TNF cluster (G-308A TNF-alpha and G+252A TNF-beta), associated with increased TNF-alpha production, were shown to be in tight linkage disequilibrium with the class I and II HLA loci, generating HLA haplotypes with extended linkage disequilibrium. However, no age-related allele or genotype frequencies were observed for either polymorphic nucleotide."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.org/dc/terms/identifier"doi:10.1016/s0047-6374(03)00037-x"xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Ross O.A."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Curran M.D."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Patterson C."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Middleton D."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Rea I.M."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Barnett C.R."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Barnett Y.A."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Annett K."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Duggan O."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/author"Hyland P."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/name"Mech Ageing Dev"xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/pages"563-567"xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/title"HLA haplotypes and TNF polymorphism do not associate with longevity in the Irish."xsd:string
http://purl.uniprot.org/citations/12714268http://purl.uniprot.org/core/volume"124"xsd:string
http://purl.uniprot.org/citations/12714268http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12714268
http://purl.uniprot.org/citations/12714268http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12714268
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12714268
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12714268
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12714268
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12714268
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-12714268http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12714268