| http://purl.uniprot.org/citations/12717433 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12717433 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12717433 | http://www.w3.org/2000/01/rdf-schema#comment | "The gene Bcl11b, which encodes zinc finger proteins, and its paralog, Bcl11a, are associated with immune-system malignancies. We have generated Bcl11b-deficient mice that show a block at the CD4-CD8-double-negative stage of thymocyte development without any impairment in cells of B- or gammadelta T cell lineages. The Bcl11b-/-thymocytes showed unsuccessful recombination of V(beta) to D(beta) and lacked the pre-T cell receptor (TCR) complex on the cell surface, owing to the absence of Tcrb mRNA expression. In addition, we saw profound apoptosis in the thymus of neonatal Bcl11b-/-mice. These results suggest that Bcl11b is a key regulator of both differentiation and survival during thymocyte development."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni927"xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni927"xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Aizawa S."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Aizawa S."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Inoue J."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Inoue J."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Mishima Y."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Mishima Y."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Takeda N."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Takeda N."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Watanabe H."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Watanabe H."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Niwa O."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Niwa O."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Wakabayashi Y."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Wakabayashi Y."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Sakata J."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Sakata J."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Hitomi J."xsd:string |
| http://purl.uniprot.org/citations/12717433 | http://purl.uniprot.org/core/author | "Hitomi J."xsd:string |