http://purl.uniprot.org/citations/12718882 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12718882 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12718882 | http://www.w3.org/2000/01/rdf-schema#comment | "The essential splicing factors SF1 and U2AF play an important role in the recognition of the pre-mRNA 3' splice site during early spliceosome assembly. The structure of the C-terminal RRM (RRM3) of human U2AF(65) complexed to an N-terminal peptide of SF1 reveals an extended negatively charged helix A and an additional helix C. Helix C shields the potential RNA binding surface. SF1 binds to the opposite, helical face of RRM3. It inserts a conserved tryptophan into a hydrophobic pocket between helices A and B in a way that strikingly resembles part of the molecular interface in the U2AF heterodimer. This molecular recognition establishes a paradigm for protein binding by a subfamily of noncanonical RRMs."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00115-1"xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00115-1"xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Sprangers R."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Sprangers R."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Sattler M."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Sattler M."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Stier G."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Stier G."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Kraemer A."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Kraemer A."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Selenko P."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Selenko P."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Gregorovic G."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Gregorovic G."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Rhani Z."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/author | "Rhani Z."xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/pages | "965-976"xsd:string |
http://purl.uniprot.org/citations/12718882 | http://purl.uniprot.org/core/pages | "965-976"xsd:string |