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http://purl.uniprot.org/citations/12736766 | http://www.w3.org/2000/01/rdf-schema#comment | "This study examines the effects of inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) on acetylcholine (ACh)-induced contraction in rat urinary bladder smooth muscle. Neostigmine, a non-selective ChE inhibitor, caused concentration-dependent contractions in rat urinary bladder strips, whereas tetraisopropylpyrophosphoramide (iso-OMPA; a BuChE inhibitor) failed to affect the resting tone of the preparations. Neostigmine (1 microM) markedly augmented the contractile responses to ACh. Although iso-OMPA (10 microM) also potentiated ACh-induced contraction, the effect was less than that evoked by neostigmine. The activities of AChE in rat urinary bladder strips were significantly (P<0.05) higher than those of BuChE. These results indicated that AChE, rather than BuChE, plays an important role in controlling ACh-induced contractions of rat urinary bladder."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00240-003-0326-1"xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/author | "Ishii K."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/author | "Kubota Y."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/author | "Sakamoto K."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/author | "Nakahara T."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/name | "Urol Res"xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/pages | "223-226"xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/title | "The role of cholinesterases in rat urinary bladder contractility."xsd:string |
http://purl.uniprot.org/citations/12736766 | http://purl.uniprot.org/core/volume | "31"xsd:string |
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