http://purl.uniprot.org/citations/12738765 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12738765 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12738765 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/12738765 | http://www.w3.org/2000/01/rdf-schema#comment | "RbsD is the only protein whose biochemical function is unknown among the six gene products of the rbs operon involved in the active transport of ribose. FucU, a paralogue of RbsD conserved from bacteria to human, is also the only protein whose function is unknown among the seven gene products of the l-fucose regulon. Here we report the crystal structures of Bacillus subtilis RbsD, which reveals a novel decameric toroidal assembly of the protein. Nuclear magnetic resonance and other studies on RbsD reveal that the intersubunit cleft of the protein binds specific forms of d-ribose, but it does not have an enzyme activity toward the sugar. Likewise, FucU binds l-fucose but lacks an enzyme activity toward this sugar. We conclude that RbsD and FucU are cytoplasmic sugar-binding proteins, a novel class of proteins whose functional role may lie in helping influx of the sugar substrates."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m304523200"xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m304523200"xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Lee H.-S."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Lee H.-S."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Shin J."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Shin J."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Lee W."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Lee W."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Kim M.-S."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Kim M.-S."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Oh B.-H."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/author | "Oh B.-H."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/pages | "28173-28180"xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/pages | "28173-28180"xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/title | "Crystal structures of RbsD leading to the identification of cytoplasmic sugar-binding proteins with a novel folding architecture."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/title | "Crystal structures of RbsD leading to the identification of cytoplasmic sugar-binding proteins with a novel folding architecture."xsd:string |
http://purl.uniprot.org/citations/12738765 | http://purl.uniprot.org/core/volume | "278"xsd:string |