http://purl.uniprot.org/citations/12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12750251 | http://www.w3.org/2000/01/rdf-schema#comment | "Ionizing radiation (IR) is a well-characterized carcinogen in humans and mice. The BALB/c mouse strain is unusually sensitive to IR-induced tissue damage and cancer development in a range of organs, suggestive of a partial defect in DNA damage response. This has been confirmed by finding BALB/c-specific functional polymorphism in Prkdc, a gene on mouse chromosome 16 that encodes the catalytic subunit of DNA-dependent protein kinase. Prkdc(BALB) has been associated with increased susceptibility to IR-induced mammary and lymphatic neoplasia. Here, we provide evidence that chromosome 16 segments from BALB/c interact with Apc(Min) (multiple intestinal neoplasia) and specifically enhance IR-induced adenoma development in the upper part of the small intestine."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Edwards A."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Cox R."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Weil M.M."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Haines J."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Silver A."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Moody J."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Ellender M."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Coster M."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/author | "Degg N.L."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/name | "Cancer Res"xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/pages | "2361-2363"xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/title | "Adenoma multiplicity in irradiated Apc(Min) mice is modified by chromosome 16 segments from BALB/c."xsd:string |
http://purl.uniprot.org/citations/12750251 | http://purl.uniprot.org/core/volume | "63"xsd:string |
http://purl.uniprot.org/citations/12750251 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12750251 |
http://purl.uniprot.org/citations/12750251 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12750251 |
http://purl.uniprot.org/uniprot/#_B2RUG9-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_E9QLQ9-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_F6Z405-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_P70382-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_E9Q4H1-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_F6Q4R2-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |
http://purl.uniprot.org/uniprot/#_Q8BRD8-mappedCitation-12750251 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12750251 |