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http://purl.uniprot.org/citations/12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12750251http://www.w3.org/2000/01/rdf-schema#comment"Ionizing radiation (IR) is a well-characterized carcinogen in humans and mice. The BALB/c mouse strain is unusually sensitive to IR-induced tissue damage and cancer development in a range of organs, suggestive of a partial defect in DNA damage response. This has been confirmed by finding BALB/c-specific functional polymorphism in Prkdc, a gene on mouse chromosome 16 that encodes the catalytic subunit of DNA-dependent protein kinase. Prkdc(BALB) has been associated with increased susceptibility to IR-induced mammary and lymphatic neoplasia. Here, we provide evidence that chromosome 16 segments from BALB/c interact with Apc(Min) (multiple intestinal neoplasia) and specifically enhance IR-induced adenoma development in the upper part of the small intestine."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Edwards A."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Cox R."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Weil M.M."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Haines J."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Silver A."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Moody J."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Ellender M."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Coster M."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/author"Degg N.L."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/name"Cancer Res"xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/pages"2361-2363"xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/title"Adenoma multiplicity in irradiated Apc(Min) mice is modified by chromosome 16 segments from BALB/c."xsd:string
http://purl.uniprot.org/citations/12750251http://purl.uniprot.org/core/volume"63"xsd:string
http://purl.uniprot.org/citations/12750251http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12750251
http://purl.uniprot.org/citations/12750251http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12750251
http://purl.uniprot.org/uniprot/#_B2RUG9-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_E9QLQ9-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_F6Z405-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_P70382-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_E9Q4H1-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_F6Q4R2-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251
http://purl.uniprot.org/uniprot/#_Q8BRD8-mappedCitation-12750251http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12750251