| http://purl.uniprot.org/citations/12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12762136 | http://www.w3.org/2000/01/rdf-schema#comment | "The major complication of familial Mediterranean fever (FMF) is AA amyloidosis. The influence of FMF gene (MEFV) mutations and/or unknown environmental factors and other genetic modifiers are likely to affect the phenotypic variations of the disease and the development of amyloidosis. Serum amyloid A is a serum precursor of AA amyloid that is induced by inflammatory cytokines including TNF-alpha. Our analysis of SAA1.1 frequency in Turkish FMF-amyloidosis patients, revealed a higher frequency compared to non FMF-amyloidosis patients but the difference was not significant. On the other hand, the distribution of SAA1.1 homozygosity among FMF-amyloidosis patients was 55.5% compared to FMF-non-amyloidosis patients (30.8%) which was statistically significant revealing a 2.5 fold risk for the occurrence of amyloidosis. There was no significant difference between the controls and FMF patients with and without amyloidosis for the TNF-alpha-308 G-A allele. It is worth noting that all TNF-alpha-308 G-A carriers (n = 6) in FMF-amyloidosis group have SAA1.1 homozygosity compared to 2/11 in FMF-non-amyloidosis group. Further evaluation of these polymorphisms may have importance and need further study."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.org/dc/terms/identifier | "doi:10.3109/13506120308995251"xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Yalcinkaya F."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Akar N."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Ekim M."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Akar E."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Cakar N."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/author | "Hasipek M."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/name | "Amyloid"xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/pages | "12-16"xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/title | "Serum amyloid A1 and tumor necrosis factor-alpha alleles in Turkish familial Mediterranean fever patients with and without amyloidosis."xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/12762136 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12762136 |
| http://purl.uniprot.org/citations/12762136 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12762136 |
| http://purl.uniprot.org/uniprot/#_D2DTW1-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
| http://purl.uniprot.org/uniprot/#_D2DTW2-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
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| http://purl.uniprot.org/uniprot/#_A0A1U9X8M9-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
| http://purl.uniprot.org/uniprot/#_A0A411D318-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
| http://purl.uniprot.org/uniprot/#_A0A510GFL8-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
| http://purl.uniprot.org/uniprot/#_C1K3N5-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
| http://purl.uniprot.org/uniprot/#_B5BUQ6-mappedCitation-12762136 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12762136 |
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