| http://purl.uniprot.org/citations/12767055 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12767055 | http://www.w3.org/2000/01/rdf-schema#comment | "The modulation of CD44, VCAM-1 and CD71 expression was analysed by flow cytometry in the 1321N1 astrocytoma cell line in the presence of interleukin-1beta (IL1beta), tumour necrosis factor-alpha (TNFalpha) and 1-40 or 25-35 beta-amyloid (Abeta) fragments. The percentage of 1321N1 astrocytoma cell line expressing these markers increased significantly after treatment with TNFalpha or IL1beta. The presence of Abeta 1-40 fragment, alone or in combination with IL1beta, induced an increase in the percentage of cells expressing CD44, but not VCAM-1. However, the concomitant presence of Abeta 1-40 fragment and of IL1beta or TNFalpha caused an increase in the percentage of CD71 positive cells. In contrast, the shorter Abeta 25-35 fragment was always inactive. These results indicates that Abeta 1-40 fragment, in association with cytokines, can activate this astrocyte-derived cell line and add further elements in favour of the hypothesis that beta-amyloid can act as immunological mediator."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.org/dc/terms/identifier | "doi:10.1002/jcp.10295"xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Mariani C."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Ferrante P."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Longhi R."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Calabrese E."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Saresella M."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Bava L."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Ruzzante S."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Speciale L."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/author | "Taramelli D."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/name | "J Cell Physiol"xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/pages | "190-195"xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/title | "1-40 Beta-amyloid protein fragment modulates the expression of CD44 and CD71 on the astrocytoma cell line in the presence of IL1beta and TNFalpha."xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://purl.uniprot.org/core/volume | "196"xsd:string |
| http://purl.uniprot.org/citations/12767055 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12767055 |
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