| http://purl.uniprot.org/citations/12767830 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12767830 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12767830 | http://www.w3.org/2000/01/rdf-schema#comment | "Dof is a large molecule essential for signal transduction by the two FGF receptors in Drosophila. It contains two ankyrin repeats and a coiled-coil region, but has no other recognisable structural motif. Dof shares these features with its closest vertebrate relatives, the B-cell signalling molecules BCAP and BANK. In addition, this family of proteins shares a region of homology upstream of the ankyrin repeats, which we call the Dof/BCAP/BANK (DBB) motif. We have identified 44 proteins that interact with Dof in a yeast two-hybrid screen. These include the Drosophila FGF-receptor Heartless and Dof itself. We show that the integrity of the DBB motif is required both for Dof and for BCAP to form dimers. Analysis of the interactions between a set of deletion constructs of Dof and the panel of interactors suggests that Dof may adopt different conformations, with a folded conformation stabilized by interactions between the DBB motif and the C-terminal part of the protein."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0022-2836(03)00489-3"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0022-2836(03)00489-3"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Wilson R."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Wilson R."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Battersby A."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Battersby A."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Csiszar A."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Csiszar A."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Leptin M."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/author | "Leptin M."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/pages | "479-493"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/pages | "479-493"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/title | "Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/title | "Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP."xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/volume | "329"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://purl.uniprot.org/core/volume | "329"xsd:string |
| http://purl.uniprot.org/citations/12767830 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12767830 |
| http://purl.uniprot.org/citations/12767830 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12767830 |