| http://purl.uniprot.org/citations/12778456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12778456 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo assess the association of human leucocyte antigen (HLA)-DRB1 allele with the genetic susceptibility to cirrhosis due to hepatitis B virus(HBV).MethodsOne hundred and six patients with cirrhosis due to HBV in Hubei area were investigated for HLA-DRB1 gene by polymerase chain reaction-sequence specific primers technique. The results were compared with those from 108 normal healthy people.ResultsThe frequency of HLA-DRB1*1201/1202 allele was 20.28% in patient group, which was significantly higher than the frequency (6.01%) in control group, the relative risk (RR) being 4.9878 (P<0.01). The frequency of HLA-DRB1*1501/1502 allele was decreased in patient group (patient 6.6%, control 16.67%, RR=0.3043, P<0.05), while the frequencies of other HLA-DRB1 alleles were not significantly different(P>0.05).ConclusionHLA-DRB1*1201/1202 allele may be the susceptibility gene in patients with cirrhosis due to HBV in Hubei Han nationality; HLA-DRB1*1501/1502 allele is a resistant gene in patients with cirrhosis."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/author | "Cheng Y.Q."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/author | "Xiong P."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/author | "Lin J.S."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/author | "Huang L.H."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/author | "Tian D.Y."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/name | "Zhonghua Yi Xue Yi Chuan Xue Za Zhi"xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/pages | "247-249"xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/title | "[The association of HLA-DRB1 allele polymorphism with the genetic susceptibility to liver cirrhosis due to hepatitis B virus]."xsd:string |
| http://purl.uniprot.org/citations/12778456 | http://purl.uniprot.org/core/volume | "20"xsd:string |
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| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-12778456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12778456 |
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| http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-12778456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12778456 |
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