RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12781916http://www.w3.org/2000/01/rdf-schema#comment"The present study was undertaken to investigate the hypothesis that the mu-opioid receptors play a crucial role in locomotor activity and sensitization to cocaine and morphine in wild-type and mu-opioid receptor knockout mice. Our results show that morphine and cocaine increased locomotor activity in wild-type mice, but failed to increase locomotor activity in mu-opioid receptor knockout mice, suggesting a contribution of mu-opioid receptor. Repeated morphine treatment induced sensitization in wild-type mice, but this was not observed in mu-opioid receptor knockout mice. In contrast repeated cocaine treatment produced sensitization in mu-opioid receptor knockout mice, but not in wild-type mice on day 6. However, the sensitization to cocaine was observed in mu-opioid receptor knockout and wild-type mice on day 12. These results suggest that the expression of mu-opioid receptor may contribute to locomotor sensitization induced by morphine, but that mu-opioid receptor does not play an important role in mediating sensitization to cocaine."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3940(03)00410-5"xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Lee S.Y."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Yoo J.H."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Loh H.H."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Jang C.G."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Yang E.M."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/author"Ho I.K."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/name"Neurosci Lett"xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/pages"37-40"xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/title"Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice."xsd:string
http://purl.uniprot.org/citations/12781916http://purl.uniprot.org/core/volume"344"xsd:string
http://purl.uniprot.org/citations/12781916http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12781916
http://purl.uniprot.org/citations/12781916http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12781916
http://purl.uniprot.org/uniprot/#_A0A0R4J0Z2-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_E9Q7D3-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_E9Q7D4-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_A1KZZ4-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_A1KZZ6-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_A1KZZ7-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_A1XGX2-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_A4GE58-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916
http://purl.uniprot.org/uniprot/#_E9Q270-mappedCitation-12781916http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12781916