| http://purl.uniprot.org/citations/12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12783854 | http://www.w3.org/2000/01/rdf-schema#comment | "Hes7, a bHLH gene essential for somitogenesis, displays cyclic expression of mRNA in the presomitic mesoderm (PSM). Here, we show that Hes7 protein is also expressed in a dynamic manner, which depends on proteasome-mediated degradation. Spatial comparison revealed that Hes7 and Lunatic fringe (Lfng) transcription occurs in the Hes7 protein-negative domains. Furthermore, Hes7 and Lfng transcription is constitutively up-regulated in the absence of Hes7 protein and down-regulated by stabilization of Hes7 protein. Thus, periodic repression by Hes7 protein is critical for the cyclic transcription of Hes7 and Lfng, and this negative feedback represents a molecular basis for the segmentation clock."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1092303"xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/author | "Bessho Y."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/author | "Hirata H."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/author | "Kageyama R."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/author | "Masamizu Y."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/pages | "1451-1456"xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/title | "Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock."xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/12783854 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12783854 |
| http://purl.uniprot.org/citations/12783854 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12783854 |
| http://purl.uniprot.org/uniprot/#_B2RRW2-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_A2AIX5-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_A6NI15-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_O08934-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_O09010-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_Q06330-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_Q8BKT2-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_Q01705-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_Q8BY39-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_P46531-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |
| http://purl.uniprot.org/uniprot/#_O95947-mappedCitation-12783854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12783854 |