| http://purl.uniprot.org/citations/12791997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12791997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12791997 | http://www.w3.org/2000/01/rdf-schema#comment | "Although the role of Toll-like receptors in extracellular bacterial sensing has been investigated intensively, intracellular detection of bacteria through Nod molecules remains largely uncharacterized. Here, we show that human Nod1 specifically detects a unique diaminopimelate-containing N-acetylglucosamine-N-acetylmuramic acid (GlcNAc-MurNAc) tripeptide motif found in Gram-negative bacterial peptidoglycan, resulting in activation of the transcription factor NF-kappaB pathway. Moreover, we show that in epithelial cells (which represent the first line of defense against invasive pathogens), Nod1is indispensable for intracellular Gram-negative bacterial sensing."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1084677"xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1084677"xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Zaehringer U."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Zaehringer U."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Labigne A."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Labigne A."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Boneca I.G."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Boneca I.G."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Carneiro L.A."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Carneiro L.A."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Girardin S.E."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Girardin S.E."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Philpott D.J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Philpott D.J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Bertin J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Bertin J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Sansonetti P.J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Sansonetti P.J."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "DiStefano P.S."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "DiStefano P.S."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Taha M.K."xsd:string |
| http://purl.uniprot.org/citations/12791997 | http://purl.uniprot.org/core/author | "Taha M.K."xsd:string |