| http://purl.uniprot.org/citations/12799427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12799427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12799427 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified two novel proteins that interact specifically with the C-terminal repression domain of Interferon Regulatory Factor-2 (IRF-2). These proteins, which we term IRF-2 binding proteins 1 and 2 (IRF-2BP1 and IRF-2BP2, the latter having two splicing isoforms, A and B), are nuclear proteins, and have the properties of IRF-2-dependent transcriptional co-repressors that can inhibit both enhancer-activated and basal transcription in a manner that is not dependent upon histone deacetylation. IRF-2BP1 and IRF-2BP2A/B contain an N-terminal zinc finger and a C-terminal RING finger domain of the C3HC4 subclass, but show no homology to other known transcriptional regulators; they therefore define a new family of co-repressor proteins. An alternatively spliced form of IRF-2 that lacks two amino acids (valines 177 and 178) in the central portion of the protein (IRF-2[S]) cannot bind to these co-repressors and cannot mediate repression despite having the same C-terminal repression domain as IRF-2, suggesting that the relative conformation of the DNA binding domain and the C-terminal region of IRF-2 is crucial for transcriptional repression."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkg431"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkg431"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/author | "Goodbourn S."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/author | "Goodbourn S."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/author | "Childs K.S."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/author | "Childs K.S."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/pages | "3016-3026"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/pages | "3016-3026"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/title | "Identification of novel co-repressor molecules for interferon regulatory factor-2."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/title | "Identification of novel co-repressor molecules for interferon regulatory factor-2."xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/12799427 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12799427 |
| http://purl.uniprot.org/citations/12799427 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12799427 |
| http://purl.uniprot.org/citations/12799427 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12799427 |
| http://purl.uniprot.org/citations/12799427 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12799427 |
| http://purl.uniprot.org/embl-cds/AAP78945.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12799427 |
| http://purl.uniprot.org/uniprot/P14316 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12799427 |