http://purl.uniprot.org/citations/12801613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12801613 | http://www.w3.org/2000/01/rdf-schema#comment | "High PAI-1 levels post acute myocardial infarction (AMI) are associated with a poor outcome. Concentrations of insulin-like molecules, proinflammatory cytokines and an insertion (5G)/deletion (4G) polymorphism in the promoter of the PAI-1 gene, all influence circulating PAI-1 levels. We studied the determinants of PAI-1 in 123 patients immediately following and at 6 months after AMI. Within 24 h of AMI, PAI-1 levels were related to those of proinsulin-like molecules but not to levels of cytokines (interleukin-1beta, interleukin-6 or tumour necrosis factor-alpha), to genotype, or to interactions between genotype and cytokine concentration. PAI-1 levels 6 months after AMI were related to concentrations of interleukin-1beta but not to genotype. We have found no evidence that subjects with the 4G/4G polymorphism have higher PAI-1 levels on admission or 6 months after AMI. In these patients, levels of PAI-1 are related to concentrations of proinsulin-like molecules and of proinflammatory cytokines."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9150(03)00095-9"xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/author | "Humphries S.E."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/author | "Mohamed-Ali V."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/author | "Yudkin J.S."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/author | "Gray R.P."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/author | "Panahloo A."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/name | "Atherosclerosis"xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/pages | "297-304"xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/title | "Plasminogen activator inhibitor-1 (PAI-1) activity post myocardial infarction: the role of acute phase reactants, insulin-like molecules and promoter (4G/5G) polymorphism in the PAI-1 gene."xsd:string |
http://purl.uniprot.org/citations/12801613 | http://purl.uniprot.org/core/volume | "168"xsd:string |
http://purl.uniprot.org/citations/12801613 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12801613 |
http://purl.uniprot.org/citations/12801613 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12801613 |
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