| http://purl.uniprot.org/citations/12801647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12801647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12801647 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified two novel human SCAN domain genes ZNF396 and ZNF397, which are clustered within the region of chromosome 18q12. Three isoforms of ZNF396 transcript, 1.5, 2.5 and 3.9-kb, are expressed highly in liver. Four isoforms of ZNF397 transcript, 1.7, 2.5, 7.0 and 9.0-kb, are expressed in a variety of tissues, with varying levels. The SCAN-(C(2)H(2))(X) genes encode two distinct proteins due to a unique alternative splicing mechanism. Both ZNF396-fu (full zinc fingers) and ZNF397-fu consist of a SCAN domain in the N-terminal region and many consecutive C(2)H(2) zinc finger repeats in the C-terminal region. ZNF396-nf (no zinc fingers) and ZNF397-nf encode 210 and 198 amino acids, respectively, containing the SCAN domain only. ZNF396-fu, ZNF396-nf, ZNF397-fu or ZNF397-nf can homo-associate, while ZNF396-fu hetero-associates with ZNF396-nf, and ZNF397-fu hetero-associates with ZNF397-nf. ZNF396-nf and ZNF397-nf polypeptides are expressed diffusely in the cells, while ZNF396-fu and ZNF397-fu polypeptides target specifically to the nuclei. ZNF396-fu, ZNF396-nf and ZNF397-nf can repress reporter gene transcription, with ZNF397-nf having the strongest repression activity. Deletion analysis revealed that ZNF397-fu is a transcriptional activator without its nine zinc finger repeats."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(03)00551-1"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(03)00551-1"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Zhao S."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Zhao S."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Yu L."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Yu L."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Zhou G."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Zhou G."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Bi G."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Bi G."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Luo K."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/author | "Luo K."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/pages | "193-201"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/pages | "193-201"xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/title | "Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397."xsd:string |
| http://purl.uniprot.org/citations/12801647 | http://purl.uniprot.org/core/title | "Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397."xsd:string |