| http://purl.uniprot.org/citations/12804568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12804568 | http://www.w3.org/2000/01/rdf-schema#comment | "Coculture of mouse bone marrow-derived mast cells (BMMC) with fibroblasts in the presence of stem cell factor (SCF) facilitates morphological and functional maturation toward a connective tissue mast cell (CTMC)-like phenotype. By means of cDNA subtraction, we identified several inducible genes during this mast cell maturation process. Of approximately 100 sequenced clones induced, nearly 50% were chromosome 14-associated serine proteases. Approximately 14% encoded NDRG1, a 43-kDa cytosolic protein that has been implicated in cell differentiation. NDRG1 was distributed in the cytosol of cultured mast cells and CTMC in rat skin. Overexpression of NDRG1 in RBL-2H3 cells resulted in enhanced degranulation in response to various stimuli. Thus, NDRG1 may be a mast cell maturation-associated inducible protein that allows the cells to be susceptible to extracellular stimuli leading to degranulation. Additionally, several unique maturation-associated inducible genes were identified, molecular and functional characterization of which will provide new insights into mast cell biology."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(03)00942-2"xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Chang H.W."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Murakami M."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Saito T."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Miyazawa S."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Natori Y."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Hisada M."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Kikuchi-Yanoshita R."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Sugiki T."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Kudo I."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Suzuki-Nishimura T."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Taketomi Y."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Uchida M.K."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Ishii S.i."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/author | "Moon T.C."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/pages | "339-346"xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/title | "Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells."xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://purl.uniprot.org/core/volume | "306"xsd:string |
| http://purl.uniprot.org/citations/12804568 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12804568 |
| http://purl.uniprot.org/citations/12804568 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12804568 |
| http://purl.uniprot.org/uniprot/Q62433#attribution-36CE11C663AE3EDFB1C801442D56954A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12804568 |