| http://purl.uniprot.org/citations/12824885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12824885 | http://www.w3.org/2000/01/rdf-schema#comment | "The aim of the present study was to examine the prognostic significance of p27(Kip1) and cyclin E expression in patients with spindle-cell soft tissue sarcomas. In 46 cases of spindle-cell sarcoma including 17 pre-operative biopsy materials, the expression of p27(Kip1) and cyclin E was immunohistochemically examined. The expression of p27(Kip1) decreased in the nuclei of metastatic primary tumor cells (stage IV), whereas the expression of cyclin E increased in those lesions. On univariate analysis, when the expression of p27(Kip1) and cyclin E was analyzed together, patients with spindle-cell sarcoma exhibiting low expression of p27(Kip1) and high expression of cyclin E showed lower distant-metastasis-free survival (DMFS) and overall survival (OS) than those with other combinations of the two parameters (both P < 0.0001). Multivariate analysis revealed that patients with low p27(Kip1) and high cyclin E expression also showed a decrease in DMFS (P = 0.0007, relative risk = 21.3) and OS (P = 0.005, relative risk = 20.8). These results suggest that the combination analysis of p27(Kip1) and cyclin E expression even in biopsy specimens allows the prediction of the clinical behavior of spindle-cell sarcoma."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1349-7006.2003.tb01456.x"xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Goto Y."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Ihara K."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Ikemoto K."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Kawai S."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Sasaki K."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Kawauchi S."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/author | "Ohi R."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/name | "Cancer Sci"xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/pages | "412-417"xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/title | "The prognosis in spindle-cell sarcoma depends on the expression of cyclin-dependent kinase inhibitor p27(Kip1) and cyclin E."xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/12824885 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12824885 |
| http://purl.uniprot.org/citations/12824885 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12824885 |
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| http://purl.uniprot.org/uniprot/#_O43806-mappedCitation-12824885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12824885 |
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| http://purl.uniprot.org/uniprot/#_Q6I9V6-mappedCitation-12824885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12824885 |
| http://purl.uniprot.org/uniprot/#_Q96TE0-mappedCitation-12824885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12824885 |
| http://purl.uniprot.org/uniprot/#_Q9NYG6-mappedCitation-12824885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12824885 |