| http://purl.uniprot.org/citations/12833156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12833156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12833156 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice deficient in the B cell adaptor for phosphoinositide 3-kinase (BCAP) have reduced numbers of mature B lymphocytes, which show defects in cell survival and proliferation. We found here that the NF-kappa B (Rel) pathway was impaired in BCAP-deficient mature B cells and that NF-kappa B target genes, indispensable for cell survival and division, were not induced in response to B cell receptor (BCR) stimulation. Among the NF-kappa B (Rel) family, expression of c-Rel was specifically reduced in BCAP-deficient B cells. Retrovirus-mediated reintroduction of c-Rel restored the pool size of immunoglobulin (Ig)M(lo)IgD(hi) mature B cells in the spleen as well as proliferative responses to BCR stimulation. These results indicate BCAP is essential in the maintenance of mature B cells through functional coupling with c-Rel."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni949"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni949"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/author | "Kurosaki T."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/author | "Kurosaki T."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/pages | "780-786"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/pages | "780-786"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/title | "Contribution of BCAP to maintenance of mature B cells through c-Rel."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/title | "Contribution of BCAP to maintenance of mature B cells through c-Rel."xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/12833156 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12833156 |
| http://purl.uniprot.org/citations/12833156 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12833156 |
| http://purl.uniprot.org/citations/12833156 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12833156 |
| http://purl.uniprot.org/citations/12833156 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12833156 |
| http://purl.uniprot.org/uniprot/Q9EQ32 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12833156 |
| http://purl.uniprot.org/uniprot/Q9EQ32#attribution-BB211C171799E724ECF32DB7CB303A45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12833156 |