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http://purl.uniprot.org/citations/12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12859597http://www.w3.org/2000/01/rdf-schema#comment"Caucasians carry TNFA-308*2 in the 8.1 ancestral haplotype (AH) (HLA-A1,B8,DR3). In Gambians, TNFA-308*2 occurs without HLA-B8 or -DR3, suggesting an independent effect of TNFA-308 on disease. Hence we sought a segment of the 8.1 AH in Gambians. BAT1 (intron 10)*2 was selected as a specific marker of the haplotype and was found with TNFA-308*2 in Gambians. Samples homozygous at TNFA-308 and BAT1 (intron 10) demonstrated identity between the African TNFA-308*2 haplotype, the 8.1AH and the Asian diabetogenic 58.1AH (HLA-A33,B58,DR3) across a region spanning BAT1, ATP6G, IKBL, LTA, TNFA, LTB, LST-1 and AIF-1. Conservation of this block in geographically distinct populations suggests a common evolutionary origin and challenges current views of the role of TNFA-308*2 in disease."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.org/dc/terms/identifier"doi:10.1034/j.1399-0039.2003.00083.x"xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Jaye A."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Chase D."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Sirugo G."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"McDermid J."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Price P."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Yindom L.M."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Whittle H."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Bolitho P."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/author"Glasson M."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/name"Tissue Antigens"xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/pages"72-75"xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/title"A Gambian TNF haplotype matches the European HLA-A1,B8,DR3 and Chinese HLA-A33,B58,DR3 haplotypes."xsd:string
http://purl.uniprot.org/citations/12859597http://purl.uniprot.org/core/volume"62"xsd:string
http://purl.uniprot.org/citations/12859597http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12859597
http://purl.uniprot.org/citations/12859597http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12859597
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597
http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-12859597http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12859597