| http://purl.uniprot.org/citations/12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12860389 | http://www.w3.org/2000/01/rdf-schema#comment | "Prostaglandin (PG) E2 release is induced in pulmonary A549 cells by the NF-kappaB-activating stimuli interleukin-1beta (IL-1beta) and phorbol 12-myristate 13-acetate (PMA). Adenoviral over-expression of IkappaBalphaDeltaN, a dominant NF-kappaB inhibitor, prevents NF-kappaB-dependent transcription and was used to qualify the role of NF-kappaB in the release of PGE2. IkappaBalphaDeltaN repressed IL-1beta-induced, but not PMA-induced, cycloxygenase-2 (COX-2) and microsomal prostaglandin E synthase (mPGES) expression. These data conclusively demonstrate a substantial role for NF-kappaB in the co-ordinate induction of COX-2, mPGES and in the corresponding release of PGE2 by IL-1beta. However, other pathways are primarily responsible for PGE2 release induced by PMA."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(03)00672-0"xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Cambridge L.M."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Barnes P.J."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Newton R."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Holden N."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Slater D.M."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Bergmann M.W."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Catley M.C."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Chivers J.E."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Loser P."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/author | "Staples K.J."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/pages | "75-79"xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/title | "IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase."xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://purl.uniprot.org/core/volume | "547"xsd:string |
| http://purl.uniprot.org/citations/12860389 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12860389 |
| http://purl.uniprot.org/citations/12860389 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12860389 |
| http://purl.uniprot.org/uniprot/#_D9MWI3-mappedCitation-12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12860389 |
| http://purl.uniprot.org/uniprot/#_A0A510GAG5-mappedCitation-12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12860389 |
| http://purl.uniprot.org/uniprot/#_A0A510GAH8-mappedCitation-12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12860389 |
| http://purl.uniprot.org/uniprot/#_A0AA51YZX7-mappedCitation-12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12860389 |
| http://purl.uniprot.org/uniprot/#_B5BUQ8-mappedCitation-12860389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12860389 |