| http://purl.uniprot.org/citations/1286943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
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| http://purl.uniprot.org/citations/1286943 | http://www.w3.org/2000/01/rdf-schema#comment | "A potent toxin has been purified from the venom of the scorpion Centruroides sculpturatus Ewing using the ion-exchange resin CM-Sepharose CL-6B at basic pH. The toxin, designated CsE M1, comprised 65 amino acid residues and its primary structure was established as: Lys-Glu-Gly-Tyr-Leu-Val-Asn-Ser-Tyr-Thr10-Gly-Cys-Lys-Tyr-Glu-Cys- Leu-Lys-Leu-Gly20-Asp-Asn-Asp-Tyr-Cys-Leu-Arg-Glu-Cys-Arg30-Gln-Gln-Tyr-Gly-Lys-Ser-Gly-Gly - Tyr-Cys40-Tyr-Ala-Phe-Ala-Cys-Trp-Cys-Thr-His-Leu50-Tyr-Glu-Gln-Ala-Val-Val-Trp - Pro-Leu-Pro60-Asn-Lys-Thr-Cys-Asn. CsE M1 is the most lethal protein to be identified in C. sculpturatus venom and the LD50 of the toxin, determined by subcutaneous injection into Swiss mice, is 87 micrograms/kg. CsE M1 shows strong structural similarity (92% positional identity) to the most potent beta-toxin, Css II, from the Mexican scorpion, Centruroides suffusus suffusus but is quite dissimilar to the previously characterized toxins with low potency isolated from C. sculpturatus Ewing."xsd:string |
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| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Conlon J.M."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Conlon J.M."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Murphy R.F."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Murphy R.F."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Pete M.J."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/author | "Pete M.J."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/name | "Int. J. Pept. Protein Res."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/name | "Int. J. Pept. Protein Res."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/pages | "582-586"xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/pages | "582-586"xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/title | "Isolation and primary structure of a potent toxin from the venom of the scorpion Centruroides sculpturatus Ewing."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/title | "Isolation and primary structure of a potent toxin from the venom of the scorpion Centruroides sculpturatus Ewing."xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/volume | "40"xsd:string |
| http://purl.uniprot.org/citations/1286943 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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| http://purl.uniprot.org/citations/1286943 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1286943 |