| http://purl.uniprot.org/citations/12885957 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12885957 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12885957 | http://www.w3.org/2000/01/rdf-schema#comment | "TBP functions in transcription initiation in all eukaryotes and in Archaebacteria. Although the 181-amino acid (aa) carboxyl (C-) terminal core of the protein is highly conserved, TBP proteins from different phyla exhibit diverse sequences in their amino (N-) terminal region. In mice, the TBP N-terminus plays a role in protecting the placenta from maternal rejection; however the presence of similar TBP N-termini in nontherian tetrapods suggests that this domain also has more primitive functions. To gain insights into the pretherian functions of the N-terminus, we investigated its phylogenetic distribution. TBP cDNAs were isolated from representative nontetrapod jawed vertebrates (zebrafish and shark), from more primitive jawless vertebrates (lamprey and hagfish), and from a prevertebrate cephalochordate (amphioxus). Results showed that the tetrapod N-terminus likely arose coincident with the earliest vertebrates. The primary structures of vertebrate N-termini indicates that, historically, this domain has undergone events involving intragenic duplication and modification of short oligopeptide-encoding DNA sequences, which might have provided a mechanism of de novo evolution of this polypeptide."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.org/dc/terms/identifier | "doi:10.1093/molbev/msg205"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.org/dc/terms/identifier | "doi:10.1093/molbev/msg205"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/author | "Schmidt E.E."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/author | "Schmidt E.E."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/author | "Bondareva A.A."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/author | "Bondareva A.A."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/name | "Mol. Biol. Evol."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/name | "Mol. Biol. Evol."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/pages | "1932-1939"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/pages | "1932-1939"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/title | "Early vertebrate evolution of the TATA-binding protein, TBP."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/title | "Early vertebrate evolution of the TATA-binding protein, TBP."xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/12885957 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12885957 |
| http://purl.uniprot.org/citations/12885957 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12885957 |
| http://purl.uniprot.org/citations/12885957 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12885957 |
| http://purl.uniprot.org/citations/12885957 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12885957 |
| http://purl.uniprot.org/uniprot/Q6Y9Q1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12885957 |
| http://purl.uniprot.org/uniprot/Q6Y9Q5 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12885957 |