| http://purl.uniprot.org/citations/12890864 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12890864 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12890864 | http://www.w3.org/2000/01/rdf-schema#comment | "Myotubularin-related protein 7 (MTMR7) is a member of the myotubularin (MTM) family. The cDNA encoding the mouse MTMR7 contains 1,983 bp, and the predicted protein has a deduced molecular mass of 75.6 kDa. Northern and Western blot analyses showed that MTMR7 is expressed mainly in brain and mouse neuroblastoma N1E-115 cells. Recombinant MTMR7 dephosphorylated the D-3 position of phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate [Ins(1,3)P2]. The substrate specificity of MTMR7 is different than other MTM proteins in that this enzyme prefers the water-soluble substrate. Immunofluorescence showed that MTMR7 is localized in Golgi-like granules and cytosol, and subcellular fractionation showed both cytoplasmic and membrane localization of MTMR7 in N1E-115 cells. An MTMR7-binding protein was found in an anti-MTMR7 immunoprecipitate from N1E-115 cells and identified as MTM-related protein 9 (MTMR9) by tandem mass spectrometry. The coiled-coil domain of MTMR9 was sufficient for binding to MTMR7. The binding of MTMR9 increased the Ins(1,3)P2 phosphatase activity of MTMR7. Our results show that MTMR7 forms a complex with MTMR9 and dephosphorylates phosphatidylinositol 3-phosphate and Ins(1,3)P2 in neuronal cells."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1333958100"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1333958100"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/author | "Mochizuki Y."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/author | "Mochizuki Y."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/author | "Majerus P.W."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/author | "Majerus P.W."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/pages | "9768-9773"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/pages | "9768-9773"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/title | "Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/title | "Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9."xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/volume | "100"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://purl.uniprot.org/core/volume | "100"xsd:string |
| http://purl.uniprot.org/citations/12890864 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12890864 |
| http://purl.uniprot.org/citations/12890864 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12890864 |
| http://purl.uniprot.org/citations/12890864 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12890864 |
| http://purl.uniprot.org/citations/12890864 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12890864 |
| http://purl.uniprot.org/uniprot/Q9Y217 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12890864 |
| http://purl.uniprot.org/uniprot/Q9Z2D0 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12890864 |